Stimulation of Tryptophanase Synthesis in Escherichia coli by Cyclic 3′,5′-Adenosine Monophosphate

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Stimulation of tryptophanase synthesis in Escherichia coli by cyclic 3',5'-adenosine monophosphate.

Cyclic 3’,5’-AMP stimulates the rate of tryptophanase synthesis in Escherichia coli treated with tris(hydroxymethyl)aminomethane and ethylenediaminetetraacetic acid and induced with tryptophan. A maximal effect occurs at 4 X low4 M cyclic 3’,5’-AMP and a half-maximal response at 1.5 X lo-4 M. The action of cyclic 3’,5’-AMP is specific for tryptophanase since the over-all rate of protein and RNA...

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Cyclic adenosine 5'-monophosphate in Escherichia coli.

INTRODUCTION ................ ROLE OF CYCLIC AMP IN REGULATION OF GENE EXPRESSION .......... A Positive Element in Gene Expression ...................................... CRP .......................... :........................................... Direct stimulation of gene expression ...................................... Possible Role As a Negative Element .........................................

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1969

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)97790-2